Series_contact_address	Study Title	Study Source	Study Source ID	Study Description	Series_contact_city	Series_contact_country	Series_contact_email	Series_contact_institute	Series_contact_name	Series_contact_zip/postal_code	Series_contributor	Series_geo_accession	Series_last_update_date	Series_overall_design	Series_platform_id	Series_platform_taxid	Series_pubmed_id	Series_relation	Sample Source ID	Series_sample_taxid	Series_status	Series_submission_date	Series_summary	Series_supplementary_file	Series_type
Lazarettgasse 14	Expression data from colorectal tumors of mice	Expression profiling by array	GSE60871	Myeloid cells can inhibit the anti-tumor responses of T cells. The mechanism for this cross-talk is not fully elucidated but is known to require STAT3.|We employed mice with conditional deletion of STAT3 in myeloid cells to investigate myeloid STAT3 functions in colitis-associated colorectal tumors in mice. We found that STAT3 is required for suppression of anti-tumor T cell responses in the tumor stroma and identified several signaling pathways in tumor cells that might be implicated in immune escape.	Vienna	Austria	markus.jeitler@meduniwien.ac.at	Medical University Vienna	"Markus,,Jeitler"	A-1090	"Paulina,,Pathria|Robert,,Eferl"	GSE60871	Feb 21 2018	Azoxymethane/Dextransulfate (AOM/DSS)-induced colitis-associated colorectal tumors were obtained from wild-type mice and mice with conditional deletion of STAT3 in myeloid cells. Tumor and stroma tissue from colorectal tumors was separated by laser-capture-microdissection and corresponding RNA was used for Affymetrix microarray experiments to identify stromal changes that depent on STAT3 signaling in the myeloid compartment.	GPL16570	10090	26137415	BioProject: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA259706	GSM1492689 GSM1492690 GSM1492691 GSM1492692 GSM1492693 GSM1492694 GSM1492695 GSM1492696 GSM1492697 GSM1492698 GSM1492699 GSM1492700	10090	Public on Feb 09 2017	Aug 28 2014	Myeloid cells can inhibit the anti-tumor responses of T cells. The mechanism for this cross-talk is not fully elucidated but is known to require STAT3.|We employed mice with conditional deletion of STAT3 in myeloid cells to investigate myeloid STAT3 functions in colitis-associated colorectal tumors in mice. We found that STAT3 is required for suppression of anti-tumor T cell responses in the tumor stroma and identified several signaling pathways in tumor cells that might be implicated in immune escape.	ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE60nnn/GSE60871/suppl/GSE60871_RAW.tar	Expression profiling by array